Immune
Health officials warn new COVID variants are immune resistant
HONOLULU(KHON2) — Since COVID-19 was first discovered, health officials have recorded dozens of mutations of the virus. And Dr. Edward Desmond, the State Laboratories Division’s Administrator, said the omicron variant called BQ1.1, is immune resistant. “Some of these new variants are less effectively neutralized by our antibodies,” Desmond explained. “But our cell-mediated immunity will protect …
IO Biosciences Awarded US Patent for GEMSTM Technology, Promising Breakthrough for Those Engineering Antibody Therapies and Therapeutic Gene-modified Immune Cells
DOYLESTOWN, Pa.–(BUSINESS WIRE)–IO Biosciences, Inc., announced today that it has been awarded its first patent for nucleic acid constructs comprising gene-editing multi-sites (GEMS) and their uses. This patent represents a departure from traditional viral gene editing methods and is ideally suited for multiple gene insertions allowing the production of complex proteins and gene-modified cell therapies …
Oxford Coronavirus Vaccine Elicits a Robust Immune Response in Older Adults
The ChAdOx1 nCov-2019 coronavirus vaccine, developed by teams at the University of Oxford, has been shown to trigger a robust immune response in healthy adults aged 56-69 and those over 70 years of age. The data, published today in The Lancet, suggest that one of the groups most vulnerable to serious illness, and death …
Oxford University’s vaccine triggers ‘protective immune response’; Melbourne race to buy masks before crackdown; 21 new cases as NSW cluster concerns grow
Scientists at Oxford University say their experimental coronavirus vaccine has been shown in an early trial to prompt a protective immune response in hundreds of people who got the shot. British researchers first began testing the vaccine in April in about 1000 people, half of whom got the experimental vaccine. Such early trials are usually …
Distinct Immune Response Profiles for COVID-19 Could Predict Disease Trajectory
Researchers from the Penn Institute of Immunology discovered three distinct immune responses to the SARS-CoV-2 infection that could help predict the trajectory of disease in severe COVID-19 patients and may ultimately inform how to best treat them.The findings were published in Science. “For patients who are hospitalized with COVID-19, there isn’t just one way …
Coronavirus: Llamas provide key to immune therapy
Image copyright University of Reading Image caption Llamas and alpacas have evolved antibodies that scientists ‘re-engineer’ in the lab As Fifi the llama munches on grass on a pasture in Reading, her immune system has provided the template for a coronavirus treatment breakthrough. Scientists from the UK’s Rosalind Franklin Institute have used Fifi’s specially evolved …
Coronavirus: Immune clue sparks treatment hope
Image copyright Getty Images UK scientists are to begin testing a treatment that it is hoped could counter the effects of Covid-19 in the most seriously ill patients. It has been found those with the most severe form of the disease have extremely low numbers of an immune cell called a T-cell. T-cells clear infection …
Immune System Discovery Could Reduce Organ Rejection
Chronic rejection of transplanted organs is the leading cause of transplant failure, and one that the field of organ transplantation has not overcome in almost six decades since the advent of immunosuppressive drugs enabled the field to flourish.Now, a new discovery led by researchers at the University of Pittsburgh School of Medicine and Houston …
Immune discovery ‘may treat all cancer’
Image copyright Science Photo Library Image caption The new technique could kill a wide range of cancer cells, including breast and prostate A newly-discovered part of our immune system could be harnessed to treat all cancers, say scientists. The Cardiff University team discovered a method of killing prostate, breast, lung and other cancers in lab …
Disruption of Immune Signaling In Utero Could Impact Susceptibility to Rotavirus
Researchers at the University of Toronto have discovered how a brief disruption to a molecular pathway in the guts of mice before they are born can compromise adult immunity to a common and often deadly intestinal virus. The researchers found that in utero inhibition of molecular signaling in the ‘lymphotoxin pathway,’ long known as …
