The shooting was reported Wednesday afternoon near Fourth Avenue and Pine Street, near Westlake Park, police tweeted.
Seattle Fire Department Chief Harold Scoggins said one person was dead and at least five people injured were taken to Harborview Medical Center.
A 9-year-old boy and a 55-year-old woman were injured in the shooting, said David Cuerpo, a spokesman with the fire department.
The child was in serious condition while the woman was in critical condition Wednesday. The woman was taken into surgery Wednesday night, according to Harborview Medical Center. Three other men who were injured were in stable condition, Cuerpo said.
The person who died in the shooting has not been identified.
The suspect appears to have been a “lone shooter,” Seattle Police Department Chief Carmen Best told reporters.
Christina Cuthbertson, who lives in a nearby building, told CNN she heard gunshots and people running away.
“Then minutes later you see tons of cop cars coming,” Cuthbertson said. “We are told to not leave the building right now.”
Chief Best told reporters there is no information connecting the two shootings at this point.