The Kennedys have had more than their share of misfortunes. Here are some of the tragedies that have killed prominent family members:
President John F. Kennedy and his brother, Sen. Robert F. Kennedy were both assassinated.
Two decades ago, a small plane crash killed JFK’s son, John F. Kennedy Jr., his wife, Carolyn Kennedy, and sister-in-law, Lauren Bessette. JFK Jr., who was piloting the plane at night, apparently became disoriented before crashing into the Atlantic off Massachusetts in 1999.
That’s not the only plane crash linked to the family.
In 1964, JFK’s brother, Sen. Edward “Ted” Kennedy, survived a plane crash that killed two people. He was on a campaign flight from Washington to Massachusetts when the plane crashed. The pilot and a legislative aide were killed and Kennedy suffered a broken back and ribs. Federal investigators blamed the crash on pilot error.
A drug overdose
A skiing accident
A failed brain surgery
An infant son dies
In 1963, President Kennedy and first lady Jacqueline Kennedy suffered yet another loss.
They announced the birth of their third child, Patrick, nearly six weeks early. He survived for less than two days and was buried in the family grave site at Arlington National Cemetery near Washington.
A cancer battle
Cancer has also played a role in the Kennedy family tragedies.
“The Kennedy family has had to endure these things in a very open way. But our family is just like … every other family in America in many ways,” he said.
CNN’s Thom Patterson contributed to this report.